STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSIP1PC4 and SFRS1-interacting protein; Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis (By similarity). (530 aa)    
Predicted Functional Partners:
MEN1
Menin 1.
    
 
 0.936
POGZ
Pogo transposable element derived with ZNF domain.
    
 
 0.902
SMC3
Structural maintenance of chromosomes protein.
   
 
 0.826
SRSF1
Uncharacterized protein.
   
 
 0.767
CPSF6
Cleavage and polyadenylation specific factor 6.
      
 0.755
KMT2B
Lysine methyltransferase 2B.
    
 
 0.749
KMT2A
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
    
 
 0.749
TNPO3
Transportin 3.
   
  
 0.702
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
   
 
 0.679
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
      
 0.637
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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