STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRY3Sprouty RTK signaling antagonist 3. (288 aa)    
Predicted Functional Partners:
CBL
Cbl proto-oncogene.
    
 0.706
CBLC
Cbl proto-oncogene C.
    
 0.706
CBLB
Cbl proto-oncogene B.
    
 0.706
CHCHD4
CHCH domain-containing protein.
      
 0.703
TMLHE
Trimethyllysine hydroxylase, epsilon.
      
 0.700
UROC1
Urocanate hydratase 1.
      
 0.668
SLC41A2
Solute carrier family 41 member 2.
      
 0.634
PPP2R2A
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
      
 0.634
GRIP2
Glutamate receptor interacting protein 2.
      
 0.617
APBB1IP
Amyloid beta precursor protein binding family B member 1 interacting protein.
      
 0.614
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.