STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIMP4TIMP metallopeptidase inhibitor 4. (224 aa)    
Predicted Functional Partners:
MMP9
Matrix metallopeptidase 9.
    
 0.766
MMP8
Matrix metallopeptidase 8.
    
 0.750
MMP7
Matrilysin; Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase; Belongs to the peptidase M10A family.
    
 0.636
MMP14
Matrix metallopeptidase 14.
    
 0.632
MMP28
Matrix metallopeptidase 28.
    
 0.628
MMP13
Matrix metallopeptidase 13.
    
 0.600
MMP16
Matrix metallopeptidase 16.
    
 0.586
MMP3
Matrix metallopeptidase 3.
    
 0.570
MMP2
Matrix metallopeptidase 2.
    
 0.570
MMP10
Matrix metallopeptidase 10.
    
 0.557
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.