STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RTCBRNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. (505 aa)    
Predicted Functional Partners:
FAM98B
Family with sequence similarity 98 member B.
    
 0.985
CA3H2orf49
Chromosome A3 C2orf49 homolog.
    
 0.969
ZBTB8OS
Zinc finger and BTB domain containing 8 opposite strand.
 
 0.963
DDX1
DEAD-box helicase 1.
   
 0.963
RTRAF
Uncharacterized protein.
   
 0.945
FAM98A
Family with sequence similarity 98 member A.
    
 0.836
RTCA
RNA 3'-terminal phosphate cyclase.
  
  
 0.816
SLFNL1
Schlafen like 1.
   
 0.802
RCL1
RNA terminal phosphate cyclase like 1.
  
  
 0.700
MCC
MCC regulator of WNT signaling pathway.
  
  
 0.700
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.