STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHBDL3Rhomboid-related protein 3; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family. (405 aa)    
Predicted Functional Partners:
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.714
WDR90
WD repeat domain 90.
   
 0.634
RHBDD3
Rhomboid domain containing 3.
      
 0.618
MAGI3
Membrane associated guanylate kinase, WW and PDZ domain containing 3.
  
 0.611
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
  
 0.589
CAPN12
Calpain 12; Belongs to the peptidase C2 family.
   
 
 0.574
RHBDD1
Rhomboid domain containing 1.
      
 0.529
SMTNL2
Smoothelin like 2.
    
 
 0.518
FGF11
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 
 0.508
PSMB11
Proteasome subunit beta.
   
 
 0.503
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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