STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK6Non-specific serine/threonine protein kinase. (681 aa)    
Predicted Functional Partners:
CDC42-2
Uncharacterized protein.
   
 0.984
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.963
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.958
NCK2
Cytoplasmic protein.
    
 0.956
RAC2
Rac family small GTPase 2.
   
 0.953
LIMK1
LIM domain kinase 1.
    
0.940
LIMK2
LIM domain kinase 2.
    
0.939
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
0.926
GNG12
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
     
  0.924
ROBO1
Roundabout guidance receptor 1.
   
 0.920
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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