STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DSTNDestrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (171 aa)    
Predicted Functional Partners:
LIMK1
LIM domain kinase 1.
   
 0.698
LIMK2
LIM domain kinase 2.
   
 0.696
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
  
 
0.659
WDR1
WD repeat domain 1.
   
 
 0.636
FUNDC2
FUN14 domain containing 2.
   
  
 0.636
CAP1
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.599
CAP2
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.599
TIMM17A
Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
   
  
 0.592
PDAP1
PDGFA associated protein 1.
   
  
 0.582
LOC101101369
Uncharacterized protein; Belongs to the profilin family.
   
 0.578
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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