STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TPX2TPX2 microtubule nucleation factor. (748 aa)    
Predicted Functional Partners:
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.982
COG3
Component of oligomeric golgi complex 3.
    
 0.907
COG5
Component of oligomeric golgi complex 5.
   
 0.907
COG2
Component of oligomeric golgi complex 2.
    
 0.905
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
 0.904
COG1
Component of oligomeric golgi complex 1.
    
 0.903
COG8
Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family.
   
 0.902
NUSAP1
Nucleolar and spindle associated protein 1.
   
  
 0.889
COG4
Component of oligomeric golgi complex 4.
    
 0.812
SMIM7
Small integral membrane protein 7.
    
 0.812
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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