STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HHIPHedgehog interacting protein. (682 aa)    
Predicted Functional Partners:
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.998
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.989
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.989
PTCH1
Patched 1.
    
 
 0.754
GLI1
GLI family zinc finger 1.
      
 0.657
SORL1
Sortilin related receptor 1.
    
 0.649
GLI3
GLI family zinc finger 3.
      
 0.646
SMO
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.638
PTCH2
Patched 2.
    
 
 0.621
GLI2
Uncharacterized protein.
      
 0.599
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.