STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)    
Predicted Functional Partners:
RAP1A
RAP1A, member of RAS oncogene family.
    
 0.989
RAP1B
RAP1B, member of RAS oncogene family.
    
 0.965
RAPGEF4
Rap guanine nucleotide exchange factor 4.
  
  
 
0.953
ADCY6
Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
 
 0.938
ADCY4
Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
 
 0.935
RRAS2
Uncharacterized protein.
    
 0.932
RRAS
RAS related.
    
 0.932
ADCY2
Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
 
 0.930
ADCY5
Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
   
 
 0.928
ADCY8
Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
 
 0.926
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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