STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CIAO2ACytosolic iron-sulfur assembly component 2A. (160 aa)    
Predicted Functional Partners:
CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family.
    
 0.973
MMS19
MMS19 homolog, cytosolic iron-sulfur assembly component.
    
 0.963
CIAO3
Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family.
    
 0.759
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit.
    
 0.697
NARF
Nuclear prelamin A recognition factor; Belongs to the NARF family.
    
 0.639
FBXL5
F-box and leucine rich repeat protein 5.
    
 
 0.600
CIAO2B
Cytosolic iron-sulfur assembly component 2B.
  
 
0.508
DDX11
DEAD/H-box helicase 11.
    
 0.447
BRIP1
BRCA1 interacting protein C-terminal helicase 1.
    
 0.447
ENSFCAP00000052399
Uncharacterized protein.
    
 0.447
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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