Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but at higher resolution
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DYRK1A | RNF169 | ENSFCAP00000042790 | ENSFCAP00000041496 | Dual specificity tyrosine phosphorylation regulated kinase 1A. | Ring finger protein 169. | 0.743 |
ENSFCAP00000026617 | ENSFCAP00000035020 | ENSFCAP00000026617 | ENSFCAP00000035020 | Ubiquitin-like domain-containing protein. | RING-type domain-containing protein. | 0.763 |
ENSFCAP00000026617 | RNF168 | ENSFCAP00000026617 | ENSFCAP00000017340 | Ubiquitin-like domain-containing protein. | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] | 0.763 |
ENSFCAP00000026617 | RNF169 | ENSFCAP00000026617 | ENSFCAP00000041496 | Ubiquitin-like domain-containing protein. | Ring finger protein 169. | 0.696 |
ENSFCAP00000026617 | RNF8 | ENSFCAP00000026617 | ENSFCAP00000040478 | Ubiquitin-like domain-containing protein. | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] | 0.992 |
ENSFCAP00000026617 | TP53BP1 | ENSFCAP00000026617 | ENSFCAP00000019469 | Ubiquitin-like domain-containing protein. | Tumor protein p53 binding protein 1. | 0.817 |
ENSFCAP00000026617 | USP7 | ENSFCAP00000026617 | ENSFCAP00000034512 | Ubiquitin-like domain-containing protein. | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. | 0.989 |
ENSFCAP00000035020 | ENSFCAP00000026617 | ENSFCAP00000035020 | ENSFCAP00000026617 | RING-type domain-containing protein. | Ubiquitin-like domain-containing protein. | 0.763 |
ENSFCAP00000035020 | MDC1 | ENSFCAP00000035020 | ENSFCAP00000007127 | RING-type domain-containing protein. | Mediator of DNA damage checkpoint 1. | 0.793 |
ENSFCAP00000035020 | RNF169 | ENSFCAP00000035020 | ENSFCAP00000041496 | RING-type domain-containing protein. | Ring finger protein 169. | 0.688 |
ENSFCAP00000035020 | RNF8 | ENSFCAP00000035020 | ENSFCAP00000040478 | RING-type domain-containing protein. | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] | 0.818 |
ENSFCAP00000035020 | SLF1 | ENSFCAP00000035020 | ENSFCAP00000023958 | RING-type domain-containing protein. | SMC5-SMC6 complex localization factor 1. | 0.569 |
ENSFCAP00000035020 | TP53BP1 | ENSFCAP00000035020 | ENSFCAP00000019469 | RING-type domain-containing protein. | Tumor protein p53 binding protein 1. | 0.808 |
ENSFCAP00000035020 | USP7 | ENSFCAP00000035020 | ENSFCAP00000034512 | RING-type domain-containing protein. | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. | 0.643 |
MDC1 | ENSFCAP00000035020 | ENSFCAP00000007127 | ENSFCAP00000035020 | Mediator of DNA damage checkpoint 1. | RING-type domain-containing protein. | 0.793 |
MDC1 | RNF168 | ENSFCAP00000007127 | ENSFCAP00000017340 | Mediator of DNA damage checkpoint 1. | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] | 0.793 |
MDC1 | RNF169 | ENSFCAP00000007127 | ENSFCAP00000041496 | Mediator of DNA damage checkpoint 1. | Ring finger protein 169. | 0.715 |
MDC1 | RNF8 | ENSFCAP00000007127 | ENSFCAP00000040478 | Mediator of DNA damage checkpoint 1. | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] | 0.968 |
MDC1 | SLF1 | ENSFCAP00000007127 | ENSFCAP00000023958 | Mediator of DNA damage checkpoint 1. | SMC5-SMC6 complex localization factor 1. | 0.831 |
MDC1 | TP53BP1 | ENSFCAP00000007127 | ENSFCAP00000019469 | Mediator of DNA damage checkpoint 1. | Tumor protein p53 binding protein 1. | 0.919 |
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