STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HAND2Heart and neural crest derivatives expressed 2. (275 aa)    
Predicted Functional Partners:
NKX2-5
NK2 homeobox 5.
   
 
 0.789
TBX5
T-box transcription factor 5.
   
 0.762
GATA4
GATA binding protein 4.
   
 0.759
PHOX2A
Paired like homeobox 2A.
   
 
 0.750
MYL7
Myosin light chain 7.
   
  
 0.716
PHOX2B
Paired like homeobox 2B.
   
 
 0.710
MEF2C
MADS-box domain-containing protein.
    
 
 0.656
ETV2
ETS variant 2.
    
 0.637
HOXB9
Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.
    
 
 0.632
GATA3
GATA binding protein 3.
   
 0.621
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.