STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEP57Centrosomal protein 57. (501 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
     
 0.858
PLK4
Polo like kinase 4.
     
 0.771
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
      
 0.764
CEP63
Centrosomal protein 63.
    
 
 0.755
CEP290
Centrosomal protein 290.
   
 
 0.751
CEP135
Centrosomal protein 135.
   
 
 0.698
ALMS1
ALMS1 centrosome and basal body associated protein.
      
 0.687
POC1B
POC1 centriolar protein B.
      
 0.618
TRIP13
Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family.
   
  
 0.605
USP47
Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family.
      
 0.596
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.