STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MARCHF8Membrane associated ring-CH-type finger 8. (569 aa)    
Predicted Functional Partners:
SERINC5
Serine incorporator 5.
   
  
 0.723
UBR1
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 
 0.685
FBXL20
F-box domain-containing protein.
   
  
 0.671
DDAH1
Dimethylarginine dimethylaminohydrolase 1.
      
 0.669
PDCD6
Programmed cell death 6.
      
 0.652
BST2
Uncharacterized protein.
    
 
 0.620
GBP1
Guanylate binding protein 1.
      
 0.616
ZFX
Uncharacterized protein.
      
 0.603
SERINC3
Serine incorporator 3.
   
  
 0.580
SAMHD1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1.
   
  
 0.565
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.