STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FOXE3Forkhead box E3. (317 aa)    
Predicted Functional Partners:
PITX3
Homeobox protein.
   
 
 0.687
PAX8
Paired box 8.
   
  
 0.636
PITX2
Paired like homeodomain 2.
   
 
 0.615
TG
Thyroglobulin.
    
 0.590
TPO
Thyroid peroxidase.
    
 
 0.581
PKIA
cAMP-dependent protein kinase inhibitor alpha.
      
 0.509
DMRTA1
DMRT like family A1.
      
 0.456
HHEX
Hematopoietically expressed homeobox.
      
 0.455
CRYAA
Alpha-crystallin A chain; Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
      
 0.424
HEY1
Hes related family bHLH transcription factor with YRPW motif 1.
      
 0.416
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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