STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERC4HECT and RLD domain containing E3 ubiquitin protein ligase 4. (1071 aa)    
Predicted Functional Partners:
ZMYM5
Zinc finger MYM-type containing 5.
    
 
 0.709
RCCD1
RCC1 domain containing 1.
    
0.705
UBE2A
Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.680
ISG15
ISG15 ubiquitin like modifier.
   
 0.659
PIGY
Uncharacterized protein.
      
 0.657
MARCHF7
Membrane associated ring-CH-type finger 7.
   
 
 0.653
FAM13A
Family with sequence similarity 13 member A.
      
 0.651
NCK2
Cytoplasmic protein.
      
 0.633
NCK1
Cytoplasmic protein.
      
 0.633
PSME4
Proteasome activator subunit 4.
   
 
 0.625
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.