STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERPINB6SERPIN domain-containing protein; Belongs to the serpin family. (396 aa)    
Predicted Functional Partners:
CTSG
Cathepsin G; Belongs to the peptidase S1 family.
   
 0.928
VTN
SMB domain-containing protein.
   
 0.605
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.597
CSTA
Cystatin-A; This is an intracellular thiol proteinase inhibitor.
   
 
 0.583
PLAU
Plasminogen activator, urokinase.
    
 0.546
SERPINA5
Serpin family A member 5; Belongs to the serpin family.
  
 
0.504
SLC4A9
Anion exchange protein.
      
 0.499
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif 7.
      
 0.499
PLAT
Plasminogen activator; Belongs to the peptidase S1 family.
    
 0.487
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
   
 0.483
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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