STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYS1Cystin 1. (168 aa)    
Predicted Functional Partners:
NPHP3
TPR_REGION domain-containing protein.
     
 0.582
SP9
Sp9 transcription factor.
      
 0.577
AQP5
Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.545
AQP2
Aquaporin 2; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.545
PKHD1
PKHD1 ciliary IPT domain containing fibrocystin/polyductin.
      
 0.497
OXCT1
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
      
 0.485
DEFB114
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.479
PFAS
Phosphoribosylformylglycinamidine synthase.
      
 0.455
LUC7L
LUC7 like.
      
 0.455
FAH
Fumarylacetoacetate hydrolase.
      
 0.455
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.