STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GADD45GGrowth arrest and DNA damage inducible gamma. (159 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.963
MAP3K4
Mitogen-activated protein kinase kinase kinase 4.
    
 0.953
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
    
 0.942
CCNB2
Cyclin B2; Belongs to the cyclin family.
    
 0.923
CCNB1
Cyclin B1; Belongs to the cyclin family.
    
 0.923
CCNB3
Uncharacterized protein; Belongs to the cyclin family.
    
 0.922
GADD45B
Growth arrest and DNA damage inducible beta.
  
 
0.919
AR
Androgen receptor.
    
 
 0.531
GADD45GIP1
GADD45G interacting protein 1.
    
 
 0.492
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
      
 0.455
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.