STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACAP2ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. (824 aa)    
Predicted Functional Partners:
RAB35
Uncharacterized protein.
    
 
 0.881
ARF6
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
    
 0.777
DENND6B
DENN domain containing 6B.
      
 0.749
OCRL
OCRL inositol polyphosphate-5-phosphatase.
    
 
 0.746
MICAL1
Microtubule associated monooxygenase, calponin and LIM domain containing 1.
   
  
 0.694
UBR1
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
    0.672
ARHGAP32
Rho GTPase activating protein 32.
   
  
 0.656
RHBDD1
Rhomboid domain containing 1.
      
 0.634
TBC1D10A
TBC1 domain family member 10A.
   
  
 0.626
RUSC2
RUN and SH3 domain containing 2.
      
 0.613
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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