STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARL15ADP ribosylation factor like GTPase 15. (244 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.824
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]
   
 0.778
GXYLT2
Glucoside xylosyltransferase 2.
    
 
 0.742
ITSN1
Intersectin 1.
    
 0.729
SNX18
Sorting nexin.
     
 0.710
MBLAC2
Metallo-beta-lactamase domain containing 2.
   
  
 0.689
INPP5J
Inositol polyphosphate-5-phosphatase J.
    
 0.688
PTP4A2
Protein tyrosine phosphatase 4A2.
   
 
 0.668
OSBP2
Oxysterol-binding protein; Belongs to the OSBP family.
    
 
 0.655
LRRC39
Leucine rich repeat containing 39.
    
 0.654
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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