STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HRKActivator of apoptosis harakiri; Promotes apoptosis. (91 aa)    
Predicted Functional Partners:
BMF
Bcl2 modifying factor.
      
 0.916
BCL2
BCL2 apoptosis regulator.
    
 
 0.851
MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog; Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis (By similarity).
    
 
 0.845
BIK
Uncharacterized protein.
      
 0.771
BCL2L1
BCL2 like 1.
    
 
 0.746
BOK
BCL2 family apoptosis regulator BOK.
    
 
 0.679
BCL2L2
BCL2 like 2.
    
 
 0.647
BBC3
Uncharacterized protein.
      
 0.538
BAK1
BCL2 antagonist/killer 1.
    
 
 0.524
BCL2A1
BCL2 related protein A1.
    
 
 0.467
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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