PHC3 protein (Felis catus) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

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[Homology]

Score

PHC3

Polyhomeotic homolog 3. (1011 aa)

Predicted Functional Partners:

CBX8

0.811

CBX4

0.761

RNF2

0.748

PCGF2

0.745

BMI1

0.745

CBX2

0.745

EED

0.727

CBX6

0.723

CBX7

0.707

PHC1

0.691

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMI1	CBX2	ENSFCAP00000027047	ENSFCAP00000042291	Polycomb complex protein BMI-1; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ub [...]	Chromobox 2.	0.966
BMI1	CBX4	ENSFCAP00000027047	ENSFCAP00000049934	Polycomb complex protein BMI-1; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ub [...]	Chromobox 4.	0.974
BMI1	CBX6	ENSFCAP00000027047	ENSFCAP00000054504	Polycomb complex protein BMI-1; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ub [...]	Chromobox 6.	0.880
BMI1	CBX7	ENSFCAP00000027047	ENSFCAP00000024437	Polycomb complex protein BMI-1; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ub [...]	Chromobox 7.	0.904
BMI1	CBX8	ENSFCAP00000027047	ENSFCAP00000049958	Polycomb complex protein BMI-1; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ub [...]	Chromobox 8.	0.975
BMI1	EED	ENSFCAP00000027047	ENSFCAP00000001477	Polycomb complex protein BMI-1; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ub [...]	Embryonic ectoderm development.	0.842
BMI1	PCGF2	ENSFCAP00000027047	ENSFCAP00000013446	Polycomb complex protein BMI-1; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ub [...]	Polycomb group ring finger 2.	0.913
BMI1	PHC1	ENSFCAP00000027047	ENSFCAP00000014167	Polycomb complex protein BMI-1; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ub [...]	Polyhomeotic homolog 1.	0.952
BMI1	PHC3	ENSFCAP00000027047	ENSFCAP00000050102	Polycomb complex protein BMI-1; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ub [...]	Polyhomeotic homolog 3.	0.745
BMI1	RNF2	ENSFCAP00000027047	ENSFCAP00000046027	Polycomb complex protein BMI-1; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ub [...]	Ring finger protein 2.	0.998
CBX2	BMI1	ENSFCAP00000042291	ENSFCAP00000027047	Chromobox 2.	Polycomb complex protein BMI-1; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ub [...]	0.966
CBX2	CBX4	ENSFCAP00000042291	ENSFCAP00000049934	Chromobox 2.	Chromobox 4.	0.959
CBX2	CBX6	ENSFCAP00000042291	ENSFCAP00000054504	Chromobox 2.	Chromobox 6.	0.816
CBX2	CBX7	ENSFCAP00000042291	ENSFCAP00000024437	Chromobox 2.	Chromobox 7.	0.786
CBX2	CBX8	ENSFCAP00000042291	ENSFCAP00000049958	Chromobox 2.	Chromobox 8.	0.968
CBX2	EED	ENSFCAP00000042291	ENSFCAP00000001477	Chromobox 2.	Embryonic ectoderm development.	0.884
CBX2	PCGF2	ENSFCAP00000042291	ENSFCAP00000013446	Chromobox 2.	Polycomb group ring finger 2.	0.981
CBX2	PHC1	ENSFCAP00000042291	ENSFCAP00000014167	Chromobox 2.	Polyhomeotic homolog 1.	0.985
CBX2	PHC3	ENSFCAP00000042291	ENSFCAP00000050102	Chromobox 2.	Polyhomeotic homolog 3.	0.745
CBX2	RNF2	ENSFCAP00000042291	ENSFCAP00000046027	Chromobox 2.	Ring finger protein 2.	0.990