TIFA protein (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

TIFA

FHA domain-containing protein. (381 aa)

Predicted Functional Partners:

TRAF6

0.954

ALPK1

0.944

THEMIS

0.701

IRAK1

0.645

MTRR

0.579

ENSFCAP00000026617

0.558

TRAF4

0.555

TRAF5

0.555

TRAF3

0.549

TRAF2

0.528

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALPK1	IRAK1	ENSFCAP00000009946	ENSFCAP00000010077	Alpha kinase 1.	Interleukin 1 receptor associated kinase 1.	0.451
ALPK1	TIFA	ENSFCAP00000009946	ENSFCAP00000051040	Alpha kinase 1.	FHA domain-containing protein.	0.944
ALPK1	TRAF6	ENSFCAP00000009946	ENSFCAP00000047805	Alpha kinase 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.636
ENSFCAP00000026617	IRAK1	ENSFCAP00000026617	ENSFCAP00000010077	Ubiquitin-like domain-containing protein.	Interleukin 1 receptor associated kinase 1.	0.585
ENSFCAP00000026617	TIFA	ENSFCAP00000026617	ENSFCAP00000051040	Ubiquitin-like domain-containing protein.	FHA domain-containing protein.	0.558
ENSFCAP00000026617	TRAF2	ENSFCAP00000026617	ENSFCAP00000000359	Ubiquitin-like domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.648
ENSFCAP00000026617	TRAF3	ENSFCAP00000026617	ENSFCAP00000035979	Ubiquitin-like domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.636
ENSFCAP00000026617	TRAF5	ENSFCAP00000026617	ENSFCAP00000028590	Ubiquitin-like domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.507
ENSFCAP00000026617	TRAF6	ENSFCAP00000026617	ENSFCAP00000047805	Ubiquitin-like domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.992
IRAK1	ALPK1	ENSFCAP00000010077	ENSFCAP00000009946	Interleukin 1 receptor associated kinase 1.	Alpha kinase 1.	0.451
IRAK1	ENSFCAP00000026617	ENSFCAP00000010077	ENSFCAP00000026617	Interleukin 1 receptor associated kinase 1.	Ubiquitin-like domain-containing protein.	0.585
IRAK1	TIFA	ENSFCAP00000010077	ENSFCAP00000051040	Interleukin 1 receptor associated kinase 1.	FHA domain-containing protein.	0.645
IRAK1	TRAF2	ENSFCAP00000010077	ENSFCAP00000000359	Interleukin 1 receptor associated kinase 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.957
IRAK1	TRAF3	ENSFCAP00000010077	ENSFCAP00000035979	Interleukin 1 receptor associated kinase 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.811
IRAK1	TRAF4	ENSFCAP00000010077	ENSFCAP00000003714	Interleukin 1 receptor associated kinase 1.	TNF receptor-associated factor.	0.535
IRAK1	TRAF5	ENSFCAP00000010077	ENSFCAP00000028590	Interleukin 1 receptor associated kinase 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.589
IRAK1	TRAF6	ENSFCAP00000010077	ENSFCAP00000047805	Interleukin 1 receptor associated kinase 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.999
MTRR	TIFA	ENSFCAP00000014011	ENSFCAP00000051040	5-methyltetrahydrofolate-homocysteine methyltransferase reductase.	FHA domain-containing protein.	0.579
THEMIS	TIFA	ENSFCAP00000009654	ENSFCAP00000051040	Thymocyte selection associated.	FHA domain-containing protein.	0.701
TIFA	ALPK1	ENSFCAP00000051040	ENSFCAP00000009946	FHA domain-containing protein.	Alpha kinase 1.	0.944