STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HYIPutative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family. (305 aa)    
Predicted Functional Partners:
PARP8
Poly [ADP-ribose] polymerase.
  
  
 0.680
GATD3A
Uncharacterized protein.
      
 0.610
CRLF3
Cytokine receptor like factor 3.
      
 0.593
SKA1
Spindle and kinetochore associated complex subunit 1.
      
 0.565
PARP3
Poly [ADP-ribose] polymerase.
      
 0.538
GLYCTK
Glycerate kinase.
     
 0.533
MTG2
Mitochondrial ribosome associated GTPase 2.
      
 0.524
DOHH
Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family.
     
 0.496
GARS1
Glycyl-tRNA synthetase.
      
 0.489
DHX34
DExH-box helicase 34.
      
 0.487
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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