STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRMDALeucine rich melanocyte differentiation associated. (236 aa)    
Predicted Functional Partners:
SF3A3
Splicing factor 3a subunit 3.
   
 0.859
SF3A1
Splicing factor 3a subunit 1.
   
 0.838
SF3B1
Splicing factor 3b subunit 1.
   
 0.836
SF3B3
Splicing factor 3b subunit 3.
    
 0.827
SF3B2
Splicing factor 3b subunit 2.
   
 0.826
PHF5A
PHD finger protein 5A.
   
 0.820
SF3B4
Splicing factor 3b subunit 4.
    
 0.818
ENSFCAP00000033817
Uncharacterized protein.
   
 0.789
SNRPE
Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development.
   
 0.789
SF3B5
Splicing factor 3B subunit 5; Belongs to the SF3B5 family.
   
 0.781
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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