F8 protein (Felis catus) - STRING interaction network

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Score

F8

Coagulation factor VIII; Belongs to the multicopper oxidase family. (2337 aa)

Predicted Functional Partners:

VWF

0.996

PROC

0.971

F2

0.916

F9

0.841

F10

0.823

PROS1

0.778

F5

0.760

MUC5B

0.729

F7

0.726

SERPINC1

0.693

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F10	F2	ENSFCAP00000013217	ENSFCAP00000017324	Coagulation factor X.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.988
F10	F5	ENSFCAP00000013217	ENSFCAP00000007547	Coagulation factor X.	Coagulation factor V; Belongs to the multicopper oxidase family.	0.987
F10	F7	ENSFCAP00000013217	ENSFCAP00000013216	Coagulation factor X.	Coagulation factor VII.	0.985
F10	F8	ENSFCAP00000013217	ENSFCAP00000053511	Coagulation factor X.	Coagulation factor VIII; Belongs to the multicopper oxidase family.	0.823
F10	F9	ENSFCAP00000013217	ENSFCAP00000006767	Coagulation factor X.	Coagulation factor IXa heavy chain; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa; Belongs to the peptidase S1 family.	0.957
F10	PROC	ENSFCAP00000013217	ENSFCAP00000051699	Coagulation factor X.	Vitamin K-dependent protein C; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family.	0.653
F10	SERPINC1	ENSFCAP00000013217	ENSFCAP00000013843	Coagulation factor X.	Serpin family C member 1; Belongs to the serpin family.	0.994
F10	VWF	ENSFCAP00000013217	ENSFCAP00000041997	Coagulation factor X.	Uncharacterized protein.	0.936
F2	F10	ENSFCAP00000017324	ENSFCAP00000013217	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor X.	0.988
F2	F5	ENSFCAP00000017324	ENSFCAP00000007547	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor V; Belongs to the multicopper oxidase family.	0.998
F2	F7	ENSFCAP00000017324	ENSFCAP00000013216	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor VII.	0.801
F2	F8	ENSFCAP00000017324	ENSFCAP00000053511	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor VIII; Belongs to the multicopper oxidase family.	0.916
F2	F9	ENSFCAP00000017324	ENSFCAP00000006767	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor IXa heavy chain; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa; Belongs to the peptidase S1 family.	0.814
F2	MUC5B	ENSFCAP00000017324	ENSFCAP00000057248	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	VWFD domain-containing protein.	0.529
F2	PROC	ENSFCAP00000017324	ENSFCAP00000051699	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Vitamin K-dependent protein C; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family.	0.957
F2	SERPINC1	ENSFCAP00000017324	ENSFCAP00000013843	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin family C member 1; Belongs to the serpin family.	0.999
F2	VWF	ENSFCAP00000017324	ENSFCAP00000041997	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.886
F5	F10	ENSFCAP00000007547	ENSFCAP00000013217	Coagulation factor V; Belongs to the multicopper oxidase family.	Coagulation factor X.	0.987
F5	F2	ENSFCAP00000007547	ENSFCAP00000017324	Coagulation factor V; Belongs to the multicopper oxidase family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.998
F5	F7	ENSFCAP00000007547	ENSFCAP00000013216	Coagulation factor V; Belongs to the multicopper oxidase family.	Coagulation factor VII.	0.701