STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111558739Cor1 domain-containing protein. (164 aa)    
Predicted Functional Partners:
BRCA2
Breast cancer type 2 susceptibility protein homolog; Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51- ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint acti [...]
    
 0.910
SYCP3
Synaptonemal complex protein 3.
  
  
 
0.902
LOC105260238
Cor1 domain-containing protein.
  
  
 
0.900
SPO11
SPO11 initiator of meiotic double stranded breaks.
      
 0.775
REC8
REC8 meiotic recombination protein.
    
 0.691
STAG3
Stromal antigen 3.
    
 0.682
DAZL
Deleted in azoospermia like.
    
 
 0.682
OGFOD1
2-oxoglutarate and iron dependent oxygenase domain containing 1.
   
 
 0.676
SYCE1
Synaptonemal complex central element protein 1.
     
 0.672
SYCE3
Synaptonemal complex central element protein 3.
     
 0.664
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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