MTBP protein (Felis catus) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

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Score

MTBP

MDM2 binding protein. (911 aa)

Predicted Functional Partners:

TICRR

0.724

TBP

0.693

MDM2

0.654

TAF1C

0.643

MRPL13

0.623

RALGPS1

0.586

AHCTF1

0.570

TOPBP1

0.560

C12orf73

0.559

DLD

0.547

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHCTF1	MTBP	ENSFCAP00000057708	ENSFCAP00000054305	AT-hook containing transcription factor 1.	MDM2 binding protein.	0.570
AHCTF1	TAF1C	ENSFCAP00000057708	ENSFCAP00000057903	AT-hook containing transcription factor 1.	TATA-box binding protein associated factor, RNA polymerase I subunit C.	0.725
C12orf73	MTBP	ENSFCAP00000013056	ENSFCAP00000054305	Chromosome 12 open reading frame 73.	MDM2 binding protein.	0.559
C12orf73	RALGPS1	ENSFCAP00000013056	ENSFCAP00000008061	Chromosome 12 open reading frame 73.	Ral GEF with PH domain and SH3 binding motif 1.	0.658
DLD	MTBP	ENSFCAP00000004133	ENSFCAP00000054305	Dihydrolipoyl dehydrogenase.	MDM2 binding protein.	0.547
MDM2	MTBP	ENSFCAP00000025067	ENSFCAP00000054305	E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein. Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation. Component of the TRIM28/KAP1-MDM2-p53/TP53 [...]	MDM2 binding protein.	0.654
MDM2	TBP	ENSFCAP00000025067	ENSFCAP00000006527	E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein. Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation. Component of the TRIM28/KAP1-MDM2-p53/TP53 [...]	TATA-box binding protein.	0.426
MRPL13	MTBP	ENSFCAP00000052997	ENSFCAP00000054305	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.	MDM2 binding protein.	0.623
MTBP	AHCTF1	ENSFCAP00000054305	ENSFCAP00000057708	MDM2 binding protein.	AT-hook containing transcription factor 1.	0.570
MTBP	C12orf73	ENSFCAP00000054305	ENSFCAP00000013056	MDM2 binding protein.	Chromosome 12 open reading frame 73.	0.559
MTBP	DLD	ENSFCAP00000054305	ENSFCAP00000004133	MDM2 binding protein.	Dihydrolipoyl dehydrogenase.	0.547
MTBP	MDM2	ENSFCAP00000054305	ENSFCAP00000025067	MDM2 binding protein.	E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein. Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation. Component of the TRIM28/KAP1-MDM2-p53/TP53 [...]	0.654
MTBP	MRPL13	ENSFCAP00000054305	ENSFCAP00000052997	MDM2 binding protein.	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.	0.623
MTBP	RALGPS1	ENSFCAP00000054305	ENSFCAP00000008061	MDM2 binding protein.	Ral GEF with PH domain and SH3 binding motif 1.	0.586
MTBP	TAF1C	ENSFCAP00000054305	ENSFCAP00000057903	MDM2 binding protein.	TATA-box binding protein associated factor, RNA polymerase I subunit C.	0.643
MTBP	TBP	ENSFCAP00000054305	ENSFCAP00000006527	MDM2 binding protein.	TATA-box binding protein.	0.693
MTBP	TICRR	ENSFCAP00000054305	ENSFCAP00000012379	MDM2 binding protein.	TOPBP1 interacting checkpoint and replication regulator.	0.724
MTBP	TOPBP1	ENSFCAP00000054305	ENSFCAP00000061271	MDM2 binding protein.	DNA topoisomerase II binding protein 1.	0.560
RALGPS1	C12orf73	ENSFCAP00000008061	ENSFCAP00000013056	Ral GEF with PH domain and SH3 binding motif 1.	Chromosome 12 open reading frame 73.	0.658
RALGPS1	MTBP	ENSFCAP00000008061	ENSFCAP00000054305	Ral GEF with PH domain and SH3 binding motif 1.	MDM2 binding protein.	0.586