node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALB | CP | ENSFCAP00000028536 | ENSFCAP00000054320 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Ceruloplasmin; Belongs to the multicopper oxidase family. | 0.672 |
ALB | HP | ENSFCAP00000028536 | ENSFCAP00000053183 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. | 0.861 |
ALB | IL1RN | ENSFCAP00000028536 | ENSFCAP00000049899 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Interleukin-1. | 0.532 |
ALB | MPO | ENSFCAP00000028536 | ENSFCAP00000030161 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Myeloperoxidase. | 0.642 |
ALB | SERPINA1 | ENSFCAP00000028536 | ENSFCAP00000058188 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | SERPIN domain-containing protein; Belongs to the serpin family. | 0.825 |
ATOX1 | ATP7A | ENSFCAP00000005592 | ENSFCAP00000017235 | Antioxidant 1 copper chaperone. | ATPase copper transporting alpha. | 0.993 |
ATOX1 | ATP7B | ENSFCAP00000005592 | ENSFCAP00000032076 | Antioxidant 1 copper chaperone. | ATPase copper transporting beta. | 0.971 |
ATOX1 | COX17 | ENSFCAP00000005592 | ENSFCAP00000005658 | Antioxidant 1 copper chaperone. | Cytochrome c oxidase copper chaperone COX17. | 0.853 |
ATOX1 | CP | ENSFCAP00000005592 | ENSFCAP00000054320 | Antioxidant 1 copper chaperone. | Ceruloplasmin; Belongs to the multicopper oxidase family. | 0.676 |
ATP7A | ATOX1 | ENSFCAP00000017235 | ENSFCAP00000005592 | ATPase copper transporting alpha. | Antioxidant 1 copper chaperone. | 0.993 |
ATP7A | ATP7B | ENSFCAP00000017235 | ENSFCAP00000032076 | ATPase copper transporting alpha. | ATPase copper transporting beta. | 0.904 |
ATP7A | COX17 | ENSFCAP00000017235 | ENSFCAP00000005658 | ATPase copper transporting alpha. | Cytochrome c oxidase copper chaperone COX17. | 0.802 |
ATP7A | CP | ENSFCAP00000017235 | ENSFCAP00000054320 | ATPase copper transporting alpha. | Ceruloplasmin; Belongs to the multicopper oxidase family. | 0.750 |
ATP7B | ATOX1 | ENSFCAP00000032076 | ENSFCAP00000005592 | ATPase copper transporting beta. | Antioxidant 1 copper chaperone. | 0.971 |
ATP7B | ATP7A | ENSFCAP00000032076 | ENSFCAP00000017235 | ATPase copper transporting beta. | ATPase copper transporting alpha. | 0.904 |
ATP7B | COX17 | ENSFCAP00000032076 | ENSFCAP00000005658 | ATPase copper transporting beta. | Cytochrome c oxidase copper chaperone COX17. | 0.650 |
ATP7B | CP | ENSFCAP00000032076 | ENSFCAP00000054320 | ATPase copper transporting beta. | Ceruloplasmin; Belongs to the multicopper oxidase family. | 0.839 |
COX17 | ATOX1 | ENSFCAP00000005658 | ENSFCAP00000005592 | Cytochrome c oxidase copper chaperone COX17. | Antioxidant 1 copper chaperone. | 0.853 |
COX17 | ATP7A | ENSFCAP00000005658 | ENSFCAP00000017235 | Cytochrome c oxidase copper chaperone COX17. | ATPase copper transporting alpha. | 0.802 |
COX17 | ATP7B | ENSFCAP00000005658 | ENSFCAP00000032076 | Cytochrome c oxidase copper chaperone COX17. | ATPase copper transporting beta. | 0.650 |