STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (448 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
    
 0.998
RBX1
Ring-box 1.
    
 0.993
ERCC6
ERCC excision repair 6, chromatin remodeling factor.
    
 0.989
CUL4A
Cullin 4A; Belongs to the cullin family.
    
 0.978
CUL4B
Cullin 4B; Belongs to the cullin family.
    
 0.966
COP1
COP1 E3 ubiquitin ligase.
    
  0.954
XPC
XPC complex subunit, DNA damage recognition and repair factor.
     
 0.938
UVSSA
UV stimulated scaffold protein A.
    
 
 0.937
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
     
 0.937
CHRNB1
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the ligand-gated ion channel (TC 1.A.9) family.
    
 0.922
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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