STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN20Protein tyrosine phosphatase non-receptor type 20. (446 aa)    
Predicted Functional Partners:
FRMPD2
FERM and PDZ domain containing 2.
 
 
 0.923
FAM81A
Family with sequence similarity 81 member A.
      
 0.734
FAM72A
Uncharacterized protein.
      
 0.727
ARHGEF5
Rho guanine nucleotide exchange factor 5.
      
 0.726
ARHGAP11A
Rho GTPase activating protein 11A.
      
 0.721
LMBR1L
Limb development membrane protein 1 like; Belongs to the LIMR family.
    
 
 0.686
TOR2A
Torsin.
     
 0.649
LRATD2
LRAT domain containing 2.
      
 0.611
SLX1A
Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.
      
 0.540
CIDEB
Cell death inducing DFFA like effector b.
      
 0.532
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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