STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTH2RParathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. (550 aa)    
Predicted Functional Partners:
PTH2
Parathyroid hormone 2.
    
 0.998
PTH
Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity).
   
 0.988
PTH1R
Parathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family.
     
 
0.978
PTHLH
Parathyroid hormone like hormone.
    
 0.832
GPR22
G protein-coupled receptor 22.
     
 0.693
GPR142
G protein-coupled receptor 142; Belongs to the G-protein coupled receptor 1 family.
     
 0.677
TBC1D22A
TBC1 domain family member 22A.
      
 0.647
GPR171
G protein-coupled receptor 171; Belongs to the G-protein coupled receptor 1 family.
      
 0.635
GHRH
Growth hormone releasing hormone.
    
 0.626
NCDN
Neurochondrin.
      
 0.614
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.