STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM189Transmembrane protein 189. (296 aa)    
Predicted Functional Partners:
UBA52
Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...]
    
 0.996
RPS27A
Ribosomal protein S27a.
   
 0.995
LOC109502223
Ubiquitin-like domain-containing protein.
   
 0.995
BIRC6
Baculoviral IAP repeat containing 6.
   
 0.978
UBE2V1
Ubiquitin conjugating enzyme E2 V1.
 
  
  0.945
UBE2K
Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.932
UBE2S
Ubiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.931
UBE2W
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.927
UBE2J1
Ubiquitin conjugating enzyme E2 J1.
   
 0.916
UBE2V2
Ubiquitin conjugating enzyme E2 V2.
 
  
  0.912
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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