STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ST14Suppression of tumorigenicity 14. (861 aa)    
Predicted Functional Partners:
ST13
ST13 Hsp70 interacting protein.
    
 
 0.869
CCDC63
Coiled-coil domain containing 63.
    
 
 0.710
MAL
Mal, T cell differentiation protein.
   
 
 0.639
KCNH3
Potassium voltage-gated channel subfamily H member 3.
      
 0.624
COX20
Cytochrome c oxidase assembly factor COX20.
      
 0.616
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]
    
 0.592
TRIM29
Tripartite motif containing 29.
    
 
 0.576
ID3
Inhibitor of DNA binding 3, HLH protein.
      
 0.549
SPINT2
Serine peptidase inhibitor, Kunitz type 2.
   
 0.543
SPINK5
Serine peptidase inhibitor, Kazal type 5.
    
 0.516
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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