STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAXXPAXX non-homologous end joining factor. (459 aa)    
Predicted Functional Partners:
NHEJ1
Non-homologous end joining factor 1.
    
 0.896
LIG4
DNA ligase.
    
 0.851
APLF
Aprataxin and PNKP like factor.
      
 0.746
SHLD2
Shieldin complex subunit 2.
      
 0.746
XRCC4
X-ray repair cross complementing 4.
     
 0.701
PRKDC
Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.
    
 0.692
CTC1
CST telomere replication complex component 1.
      
 0.676
XRCC6
X-ray repair cross complementing 6.
    
 0.665
XRCC5
X-ray repair cross complementing 5.
    
 0.665
SAE1
SUMO1 activating enzyme subunit 1.
      
 0.632
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.