STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NTHL1Nth like DNA glycosylase 1. (470 aa)    
Predicted Functional Partners:
APEX1
DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
  
 0.841
NEIL3
Nei like DNA glycosylase 3.
   
  
 0.833
APEX2
DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
  
 0.808
MUTYH
Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.
  
  
 0.679
XRCC1
X-ray repair cross complementing 1.
   
  
 0.634
NEIL1
Nei like DNA glycosylase 1.
      
 0.627
ZBTB41
Zinc finger and BTB domain containing 41.
      
 0.625
RECQL
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
      
 0.619
MLH1
MutL homolog 1.
   
 
 0.603
TRRAP
Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.
      
 0.602
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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