STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRNGranulin precursor. (596 aa)    
Predicted Functional Partners:
SORT1
Sortilin.
    
 
 0.799
CTSD
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
 0.772
CTSZ
Cathepsin Z; Belongs to the peptidase C1 family.
   
 0.716
CS
Citrate synthase; Belongs to the citrate synthase family.
   
   0.714
DRG1
Developmentally regulated GTP binding protein 1.
    
   0.701
POLE2
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
    
   0.701
SLC25A1
Solute carrier family 25 member 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.
    
   0.701
CXorf56
Chromosome X open reading frame 56.
    
   0.701
CB3H15orf40
Chromosome B3 C15orf40 homolog.
    
   0.701
LAMP1
Lysosomal associated membrane protein 1.
   
 
 0.693
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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