STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESRRGEstrogen related receptor gamma. (506 aa)    
Predicted Functional Partners:
NCOR2
Nuclear receptor corepressor 2.
    
 0.770
PPARGC1A
PPARG coactivator 1 alpha.
   
 0.726
KCTD3
Potassium channel tetramerization domain containing 3.
    
 
 0.640
NRIP1
Nuclear receptor interacting protein 1.
    
 0.633
PRLHR
Prolactin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family.
     
 0.623
NCOA1
Nuclear receptor coactivator.
    
 0.616
ESRRA
Estrogen related receptor alpha.
  
 
 
0.589
GHR
Growth hormone receptor.
      
 0.576
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.573
NCOR1
Nuclear receptor corepressor 1.
    
 0.571
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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