node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHSG | ALB | ENSFCAP00000058422 | ENSFCAP00000028536 | Alpha 2-HS glycoprotein. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.949 |
AHSG | CELA1 | ENSFCAP00000058422 | ENSFCAP00000061773 | Alpha 2-HS glycoprotein. | Chymotrypsin-like elastase family member 1; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily. | 0.469 |
AHSG | FGG | ENSFCAP00000058422 | ENSFCAP00000055064 | Alpha 2-HS glycoprotein. | Fibrinogen gamma chain. | 0.882 |
AHSG | HP | ENSFCAP00000058422 | ENSFCAP00000053183 | Alpha 2-HS glycoprotein. | Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. | 0.618 |
AHSG | LOC101095098 | ENSFCAP00000058422 | ENSFCAP00000038697 | Alpha 2-HS glycoprotein. | Uncharacterized protein. | 0.684 |
AHSG | ORM2 | ENSFCAP00000058422 | ENSFCAP00000000151 | Alpha 2-HS glycoprotein. | Lipocln_cytosolic_FA-bd_dom domain-containing protein. | 0.656 |
AHSG | PROC | ENSFCAP00000058422 | ENSFCAP00000051699 | Alpha 2-HS glycoprotein. | Vitamin K-dependent protein C; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. | 0.486 |
AHSG | SERPINA1 | ENSFCAP00000058422 | ENSFCAP00000058188 | Alpha 2-HS glycoprotein. | SERPIN domain-containing protein; Belongs to the serpin family. | 0.822 |
ALB | AHSG | ENSFCAP00000028536 | ENSFCAP00000058422 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Alpha 2-HS glycoprotein. | 0.949 |
ALB | FGG | ENSFCAP00000028536 | ENSFCAP00000055064 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Fibrinogen gamma chain. | 0.613 |
ALB | HP | ENSFCAP00000028536 | ENSFCAP00000053183 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. | 0.861 |
ALB | ORM2 | ENSFCAP00000028536 | ENSFCAP00000000151 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Lipocln_cytosolic_FA-bd_dom domain-containing protein. | 0.715 |
ALB | SERPINA1 | ENSFCAP00000028536 | ENSFCAP00000058188 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | SERPIN domain-containing protein; Belongs to the serpin family. | 0.825 |
CELA1 | AHSG | ENSFCAP00000061773 | ENSFCAP00000058422 | Chymotrypsin-like elastase family member 1; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily. | Alpha 2-HS glycoprotein. | 0.469 |
CELA1 | SERPINA1 | ENSFCAP00000061773 | ENSFCAP00000058188 | Chymotrypsin-like elastase family member 1; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily. | SERPIN domain-containing protein; Belongs to the serpin family. | 0.798 |
ELANE | HP | ENSFCAP00000057052 | ENSFCAP00000053183 | Elastase, neutrophil expressed; Belongs to the peptidase S1 family. | Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. | 0.556 |
ELANE | SERPINA1 | ENSFCAP00000057052 | ENSFCAP00000058188 | Elastase, neutrophil expressed; Belongs to the peptidase S1 family. | SERPIN domain-containing protein; Belongs to the serpin family. | 0.836 |
FGG | AHSG | ENSFCAP00000055064 | ENSFCAP00000058422 | Fibrinogen gamma chain. | Alpha 2-HS glycoprotein. | 0.882 |
FGG | ALB | ENSFCAP00000055064 | ENSFCAP00000028536 | Fibrinogen gamma chain. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.613 |
FGG | HP | ENSFCAP00000055064 | ENSFCAP00000053183 | Fibrinogen gamma chain. | Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. | 0.667 |