STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF4Rho guanine nucleotide exchange factor 4. (1059 aa)    
Predicted Functional Partners:
APC
APC regulator of WNT signaling pathway.
   
 
 0.898
CDHR5
Cadherin related family member 5.
   
  
 0.797
KHDRBS2
KH RNA binding domain containing, signal transduction associated 2.
   
  
 0.790
PCDHB7
Protocadherin beta 7.
      
 0.772
MAPRE3
Microtubule associated protein RP/EB family member 3.
      
 0.762
PTPN18
Uncharacterized protein.
      
 0.750
LGSN
Lengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family.
   
  
 0.730
RFXAP
Regulatory factor X associated protein.
      
 0.720
MGST3
Microsomal glutathione S-transferase 3.
    
 
 0.684
APC2
APC regulator of WNT signaling pathway 2.
   
 
 0.668
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.