STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADGRG5Adhesion G protein-coupled receptor G5; Belongs to the G-protein coupled receptor 2 family. (542 aa)    
Predicted Functional Partners:
ADGRA3
Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family.
    
 
0.686
PHF21A
PHD finger protein 21A.
      
 0.605
CD3H18orf25
Chromosome D3 C18orf25 homolog.
      
 0.605
MINDY2
MINDY lysine 48 deubiquitinase 2.
      
 0.605
NAA25
N(alpha)-acetyltransferase 25, NatB auxiliary subunit.
      
 0.548
ADGRF1
Adhesion G protein-coupled receptor F1; Belongs to the G-protein coupled receptor 2 family.
   
  
0.521
RRP8
Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...]
      
 0.491
P2RY10
P2Y receptor family member 10.
   
  
 0.456
MBNL3
Muscleblind like splicing regulator 3.
      
 0.455
RAB39B
RAB39B, member RAS oncogene family.
    
 
 0.455
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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