STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPRKProtein tyrosine phosphatase receptor type K. (1485 aa)    
Predicted Functional Partners:
WAC
WW domain containing adaptor with coiled-coil.
   
  
 0.669
GORAB
Golgin, RAB6 interacting.
      
 0.587
PTK7
Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.582
PKP2
Plakophilin 2.
   
 
 0.558
KIF20A
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.540
THEMIS
Thymocyte selection associated.
   
 
 0.538
PDIK1L
PDLIM1 interacting kinase 1 like; Belongs to the protein kinase superfamily.
      
 0.528
GRXCR1
Glutaredoxin and cysteine rich domain containing 1.
   
  
 0.512
EGFR
Receptor protein-tyrosine kinase.
   
 0.511
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
  
 0.509
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.