STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PANX2Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (691 aa)    
Predicted Functional Partners:
SLC18B1
Solute carrier family 18 member B1.
      
 0.923
PANX1
Pannexin; Structural component of the gap junctions and the hemichannels.
     
0.896
CALHM1
Calcium homeostasis modulator 1.
      
 0.666
ARHGEF7
Rho guanine nucleotide exchange factor 7.
      
 0.565
GRIK5
Glutamate ionotropic receptor kainate type subunit 5.
      
 0.538
P2RX7
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
      
 0.512
GP1BB
Glycoprotein Ib platelet subunit beta.
      
 0.511
HNF1A
HNF1 homeobox A.
      
 0.505
ENTPD3
Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.
      
 0.481
GJA4
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.455
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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