STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZWILCHZwilch kinetochore protein. (630 aa)    
Predicted Functional Partners:
KNTC1
Kinetochore associated 1.
   
 0.999
TMPRSS5
Zw10 kinetochore protein.
    
 0.999
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.846
ESPL1
Extra spindle pole bodies like 1, separase.
   
 
 0.835
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
 0.811
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.800
SKA1
Spindle and kinetochore associated complex subunit 1.
   
  
 0.794
MAD2L1
Mitotic arrest deficient 2 like 1.
   
 
 0.781
BUB3
BUB3 mitotic checkpoint protein.
     
 0.776
TTK
TTK protein kinase.
   
  
 0.757
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.