STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LAT2Linker for activation of T cells family member 2. (225 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.722
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
     
 0.563
SHC1
SHC adaptor protein 1.
     
 0.551
GRAP2
GRB2 related adaptor protein 2.
    
 0.533
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
   
 
  0.526
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 
  0.526
LYN
Tyrosine-protein kinase.
   
 
 0.511
SYK
Spleen associated tyrosine kinase.
   
 
 0.509
GRAP
Uncharacterized protein.
    
 0.474
SLC1A6
Amino acid transporter.
      
 0.460
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.