STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FADDFas associated via death domain. (199 aa)    
Predicted Functional Partners:
RIPK1
Receptor-interacting serine/threonine-protein kinase 1.
   
 0.997
TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1.
   
 0.997
CASP8
Caspase-8 isoform X1.
   
 0.997
FAS
Fas cell surface death receptor.
   
 0.994
RIPK3
Receptor-interacting serine/threonine-protein kinase 3 isoform X1.
   
 0.993
CASP10
Caspase 10.
   
 0.965
FASLG
Tumor necrosis factor ligand superfamily member 6.
    
 0.951
TRAF2
TNF receptor-associated factor 2 isoform X1.
   
 0.947
TNFRSF1A
TNF receptor superfamily member 1A.
   
 0.903
CFLAR
CASP8 and FADD-like apoptosis regulator isoform X1.
    
 0.893
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.