Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM216AProtein FAM216A isoform X1. (271 aa)    
Predicted Functional Partners:
SERF2
Small EDRK-rich factor 2 isoform X1.
      
 0.604
TMEM134
Transmembrane protein 134 isoform X1.
      
 0.604
DIP2B
Disco-interacting protein 2 homolog B isoform X1.
      
 0.547
TOM1L2
TOM1-like protein 2 isoform X1.
      
 0.544
SLC8B1
Solute carrier family 8 member B1.
      
 0.524
GPN3
GPN-loop GTPase 3.
   
  
 0.517
HVCN1
Voltage-gated hydrogen channel 1 isoform X1.
      
 0.493
LOC109275036
Protein PRRC2C-like.
      
 0.490
SMYD4
SET and MYND domain-containing protein 4 isoform X1.
      
 0.482
MED29
Mediator of RNA polymerase II transcription subunit 29.
      
 0.423
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.