Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEMA3CSemaphorin-3C. (751 aa)    
Predicted Functional Partners:
NRP1
Neuropilin-1 isoform X1.
  
 
 0.965
PLXND1
Plexin-D1.
    
 0.764
NRP2
Neuropilin-2 isoform X1.
    
 
 0.728
CALCR
Calcitonin receptor.
      
 0.641
SEMA3D
Semaphorin-3D.
    
   0.599
SEMA3F
Semaphorin-3F isoform X1.
    
   0.599
PLXNA2
Plexin-A2 isoform X1.
    
0.599
GATA6
Transcription factor GATA-6.
    
 
 0.565
PRDM1
PR domain zinc finger protein 1 isoform X1.
      
 0.538
MET
Hepatocyte growth factor receptor isoform X1.
   
 0.506
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (10%) [HD]